پاورپوینت بیماری وبا و مسمومیت های غذایی (pptx) 54 اسلاید
دسته بندی : پاورپوینت
نوع فایل : PowerPoint (.pptx) ( قابل ویرایش و آماده پرینت )
تعداد اسلاید: 54 اسلاید
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بيماري وبا يك اسهال حاد عفوني است كه عامل آن باسيل ويبريو كلرا است و اگزوتوكسين مترشحه از آن مسئول پيدايش علائم بيماري است .
Cholera
It is usually transmitted through faecally contaminated water or food.
Incubation period is very short ( 2 hours to 5 days ) and number of cases can rise extremely quickly, especially in over-populated communities and refugee setting.
Case fatality rate in untreated cases may reach 30 – 50% .
Cholera: historical perspectives
John Snow: identified contaminated water as the
source of cholera spreading through London in 1849.
Robert Koch: credited with identifying V. cholerae
during the fifth pandemic in 1883.
Filippo Pacini: was really the first to identify
the organism in Italy in 1854.
Vibrio cholera and other Vibrios
Family: Vibrionaceae
Genus: Vibrio
Gram-negative rods
Single polar flagellum
Rapid linear motility
Natural habitat: environmental waters
Vibrio cholerae
Structure is similar to the Enterobactericeae
O antigen (cell surface lipopolysaccharide)
H antigen (flagellar antigen)
> 150 serotypes based on the O antigen
2 serotypes are associated with Cholera
O1 and O139
Classification of Vibrio cholerae O1
Three main serotypes (based on somatic antigens)
Inaba
Ogawa
Hakojima
Two biotypes (based on phenotypic characteristics)
Classic
El Tor
non-O1 Vibrio cholerae
May cause an illness similar to cholera.
Acquired from contaminated water or seafood.
Do not cause epidemics.
Of less public health importance.
Clinical manifestations of cholera
Abrupt onset of diarrhea without strain, tenesmus,
or cramps.
Spectrum of severity -- ranges from asymptomatic
to a life-threatening, dehydrating diarrhea.
All symptoms relate to the loss of fluid in the diarrhea.